Changing the lipid profile by Tumeric, Garlic and Cinnamon in Diabetic patients Type-2

Abstract

Back ground: Diabetes mellitus (DM) is a chronic metabolic
in syndrome characterized by hyperglycemia with possible correlation to medical plants and their lipid lowering effect. Aim: the aim of present study is to find new agents with fewer side effects the therapy of DM type-2.
Material and methods: this study was performed in AL-Kadhmiya teaching hospital between April 2008- October 2009 was approved by ethic committee of college of medicine. Fifty diabetic patients (18 males and 32 females) were involved in the present study, their ages ranged (42-58) years and were randomly allocated to five groups each group was given glipizide ia addition to the one of the following agents (acarbose, turmeric, garlic and cinnamon). Blood sample were taken before treatment with these agents and after treatment for nine weeks to estimate the lipid profile, serum cholesterol, triglyceride, HDL, LDL, and VLDL levels.
Results: all the tested agents reduced both serum cholesterol and
LDL levels significantly when used in combination with glipizide but the later has no significant effect when used alone. Combination of garlic or cinnamon with glipizide decreased significantly the triglyceride at the same time combination of acarbose or garlic raised significantly the HDL levels where as turmeric is the only agent that decreased VLDL levels significantly.
Conclusions: turmeric, garlic and cinnamon proved to have hypocholesterolemic effect and the possibility to be used clinically in management of heart diseases.