FrequencyofextendedSpectrum ẞ- Lactamase(ESBLs)producing Klebsiella isolates among multi-drug resistant, causing infections in AL-Kindy hospital in Baghdad/Iraq.

Abstract

The antibiotic sensitivity pattern of extended spectrum beta lactamase (ESBL) producing Klebiella isolates was investigated.A total of 187 clinical isolates, Klebsiella showed just 25 cause of infection isolated from urine, sputum and wounds Primary sensitive screening of these isolates were carried out using disk diffusion by Kirby -Bauer, then tested for their ability to produce ESBL using disk approximation and standard rapid iodometric methods. The result of this study revealed that 25 isolates were distributed among 10(40%),8(32%), and7(28%)from urine, sputum and wounds respectively All these isolates showed resistance to antibiotic arranged between higher resistant 24(96%) to ampicillin and lower resistant 4(16%) to amikacin., 11(44%)isolates were ESBL and could resist more than 10 antibiotic used 9 of them were ESBL when detected by disk approximation method but 5 only were ESBL when detected by standard rapid iodometric method. This study therefore ,do not only proclaim the presence of ESBL producing Klebsiella in al-kindy hospital, Baghdad but also emphasizes that they are multi-drug resistant.