Bata thalassemia incidence in Baghdad city and the association with ABO blood groups

Abstract

B-thalassemia is one of the inherited disorders of hemoglobin synthesis which is caused by the reduction or absence of Bata globin chains of hemoglobin. A total of 236 cases of clinically 6-thalassemia patients were collected from thalassemia centers in Baghdad city-Iraq. This study revealed that blood group Ot was the most common group in 6-thalassemic patients followed by blood groups B and AB whereas blood groups A, O and AB were the lowest in both males and females. Concerning the age incidence, the most common ages with 6 thalassemia was 11-18 years. HPLC analysis revealed an increased level in HbA2 (>3.5-5.5). Blood analysis showed decrease levels of MCV (64-70fl), MCH (23-27 pg) and Hb (6.3-6.8g/dl) whereas RBCs and serum ferritin exhibited increased levels (5.8-6.4 and 820-1240micro/l respectively). Platelets count was normal. In conclusion, 6-thalas-semia is more incident significantly (concerning the city of Bagh-dad) among patients with blood group O, age group 11-18 years, and in males more than females.