Effects of clove oil on Apoptosis in digestive system of rats treated with Uranium

Abstract

Uranium from the environment enters the human body by ingestion with food and drink, and by inhalation of air borne U containing dust particles or aerosols.
The digestive tract is the entry for radionuclide's following the ingestion of contaminated food and small intestine is the main area of U absorption through out the gastrointestinal tract.
The study demonstrate the apoptosis in digestive organs (stomach, small intestine, large intestine and liver), and found clove oil reduce apoptotic numbers where Uranium elevated the number of apoptotic cells. The results showed an increament significant (P < 0.05) in apoptosis cells in animals treated with 75 mg/kg UN (22.8%) in liver, and showed a reduction significant (P < 0.05) in apoptosis cells in animals treated with 500mg/kg clove oil (2.04%) in small intestine compare with control.