Allium sativum, Nigella sativum, Caryophyllus dianthus and Punicagranatum in improvementof salmonellosis in experimental rabbit model.

Authors

  • Faruk H. Al. Jawad(1) 1- Prof. dept. of pharmacology and therapeutics-Al-Yarmouk university
  • Hussein A. Kadhim(2) 2-Dept.of pharmacology-Kufa college of medicine.
  • Emad SH. Mahmoud (5) 3- Dean of Al-Yarmouk university
  • Osama k. fadhil (4) 4- Dept. of pharmacology and therapeutics-Al-Yarmouk university

Keywords:

الثوم, الحبة السوداء, مرض التيفوئيد, التركيز المثبط الاصغر

Abstract

The activity of medicinal plants against induced salmonellosis in rabbit was determined in vitro by Kirby-Baur, minimal inhibitory concentration (MIC) method the results revealed that all the aqueous extract of the tested medicinal plants at a stock concentration of 2000 ng/ml had antisalmonella effect except Dianthus caryophyllus. Nigella sativum extract had the most potent effect with MIC (125 ng/ml) & both Allium sativum & punica granatum had MIC (250 ng/ml). In the mean time, a significant potentiation was obtained by double combination of chloramphenicol with Allium sativum or Punic granatum MIC (31.25 ng/ml) or with Nigella sativum MIC (15.62 ng/ml). In conclusion both Allium sativum & Nigella sativum had shown antisalmonella activity when used singly or in combination with antibiotics.

Published

2026-05-03

How to Cite

Faruk H. Al. Jawad(1), Hussein A. Kadhim(2), Emad SH. Mahmoud (5), & Osama k. fadhil (4). (2026). Allium sativum, Nigella sativum, Caryophyllus dianthus and Punicagranatum in improvementof salmonellosis in experimental rabbit model. AL-Yarmouk Journal, 7(1), 100–109. Retrieved from https://journal.al-yarmok.edu.iq/index.php/alyj/article/view/1717

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Section

Articles